Amikacin

Amikacin therapeutic monitoring measures serum concentrations of the aminoglycoside antibiotic amikacin to ensure effective antimicrobial exposure while minimising toxicity. At-home Amikacin monitoring involves timed blood sampling (typically trough and/or peak levels) and laboratory quantification, allowing clinicians to adjust dosing based on measured drug levels and patient-specific factors such as renal function and age.

This service is recommended for patients receiving amikacin therapy—especially those with impaired or changing renal function, the elderly, critically ill patients, or those on prolonged therapy—because amikacin has a narrow therapeutic window and risks of nephrotoxicity and ototoxicity. Our Dubai- and UAE-wide at-home collection integrates with bedside nursing and rapid laboratory reporting so treating physicians can make timely dose adjustments and reduce hospital visits.

• Amikacin — Trough level (pre-dose)
• Amikacin — Peak level (post-dose)
• Serum Creatinine
• Estimated GFR (eGFR)

• Before starting amikacin therapy (baseline renal function)
• At steady state — typically a trough before the 3rd or 4th dose as advised by clinician
• When adjusting dose or frequency due to clinical response
• If there is a change in renal function or co-administered nephrotoxic drugs
• If patient shows signs of toxicity (hearing loss, tinnitus, dizziness, or reduced urine output)

• Accurate therapeutic-level measurement to guide safe dosing
• Reduced risk of nephrotoxicity and ototoxicity through timely adjustments
• Convenient at-home blood collection across Dubai and the UAE
• Rapid, clinician-ready electronic reporting for prompt treatment decisions
• Integration of drug levels with renal function for individualised dosing

• At-home venous blood collection — timed samples (trough pre-dose; peak as directed)
• Provide exact time of last amikacin dose and dosing schedule to the phlebotomist
• Inform the team about current medications, known renal disease, and hearing issues
• Ensure patient is available at scheduled sample time for accurate trough/peak sampling