ANTI SPERM ANTIBODIES

The ANTI SPERM ANTIBODIES test detects and characterises antibodies produced by the immune system that bind to sperm and can impair motility, agglutinate sperm, or interfere with fertilisation. Testing can be performed directly on a semen sample (direct tests such as MAR or immunobead assays) and indirectly via serum to identify circulating anti-sperm IgA or IgG; results help explain immune-related male infertility. Home collection with discreet sample pickup and fast, accredited laboratory reporting across Dubai and the UAE makes this test convenient and private for patients seeking fertility evaluation.

This test is commonly recommended when standard semen analysis shows poor motility or agglutination, after vasectomy reversal, in cases of unexplained infertility, or following recurrent assisted reproductive technology (ART) failures. Identifying anti-sperm antibodies guides clinical decisions—ranging from medical or immunomodulatory options to selecting appropriate ART strategies such as intrauterine insemination (IUI) or IVF/ICSI—and should be interpreted alongside a fertility specialist and andrology laboratory findings.

• Semen anti-sperm antibodies (direct)
• Serum anti-sperm antibodies (indirect)
• Antibody class — IgA
• Antibody class — IgG

• After abnormal semen analysis showing low motility or sperm agglutination
• Unexplained infertility despite normal partner evaluation
• Following vasectomy reversal or testicular surgery
• After recurrent ART (IUI/IVF) failures
• History of genital tract infection, trauma, or autoimmune disorders

• Identifies immune causes of male infertility that standard semen tests may miss
• Provides antibody class information (IgA/IgG) to guide treatment choices
• Enables targeted fertility planning, including suitable ART pathways
• Discreet home sample collection with fast, reliable lab reporting across Dubai & UAE
• Reduces unnecessary interventions by clarifying immunological contributors

• Provide a fresh semen sample collected by masturbation into a sterile container
• Abstain from ejaculation for 2–5 days prior to sample collection
• Deliver the semen sample to the collection technician within 1 hour, kept at body temperature
• Inform the provider of recent fever, genitourinary infection, antibiotics, or prior surgeries