
ANTI TISSUE TRANSGLUTAMINASE IGG ANTIBODY
Author Details
Written By
Dr. Fatima Ali
MBBS, MD
Supervised By
Dr. Imran Sheikh
MBBS, DNB




ANTI TISSUE TRANSGLUTAMINASE IGG ANTIBODY
Home blood test for anti-tissue transglutaminase IgG to help detect coeliac disease risk, with convenient sample collection and fast reports across Dubai and the UAE.
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Know More About ANTI TISSUE TRANSGLUTAMINASE IGG ANTIBODY
The Anti Tissue Transglutaminase IgG Antibody test measures IgG class autoantibodies directed against tissue transglutaminase, an enzyme involved in intestinal tissue repair. Detection of anti‑tTG IgG helps identify individuals at increased risk of coeliac disease, particularly when IgA deficiency or equivocal IgA serology limits the value of standard anti‑tTG IgA tests. This home blood test offers convenient sample collection across Dubai and the UAE with laboratory analysis and fast electronic reporting.
A positive anti‑tTG IgG result suggests immune reactivity to gluten and should prompt clinical correlation and follow‑up with a gastroenterologist; definitive diagnosis of coeliac disease typically requires integration of serology, clinical findings and, when indicated, intestinal biopsy. The test is suitable for adults and children when performed while the patient is on a gluten‑containing diet, and results should always be interpreted alongside total IgA status and other relevant investigations.
Parameters Measured
- Anti-Tissue Transglutaminase IgG (anti‑tTG IgG)
- Quantitative Antibody Level (U/mL)
- Qualitative Result (Negative / Borderline / Positive)
- Total IgA (recommended check)
When to Test it?
- Persistent gastrointestinal symptoms (diarrhoea, bloating, abdominal pain)
- Unexplained iron‑deficiency anaemia or nutrient malabsorption
- First‑degree relative with coeliac disease
- Associated autoimmune conditions (type 1 diabetes, autoimmune thyroid disease)
- Poor growth or failure to thrive in children
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Benefits Includes:
- Home blood collection by trained phlebotomists across Dubai and the UAE
- Rapid laboratory processing and electronic delivery of results
- Useful screening tool when IgA serology is unreliable or IgA deficiency is suspected
- Supports timely referral and further diagnostic workup with specialists
- Minimally invasive assessment aiding early detection of coeliac disease risk
Doctor Recommended Checkups
Test requirements:
- At‑home venous or capillary blood sample collection by a trained phlebotomist
- Remain on a gluten‑containing diet prior to testing for accurate results
- No fasting required before sample collection
- Provide valid Emirates ID and signed consent for testing (guardian consent for minors)
Author Details
Written By
Dr. Fatima Ali
MBBS, MD
Supervised By
Dr. Imran Sheikh
MBBS, DNB

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