ASMA (SMOOTH MUSCLE ANTIBODY)

The ASMA (Smooth Muscle Antibody) test detects IgG autoantibodies directed against components of smooth muscle (commonly actin) in the blood. Performed on a serum sample using validated immunoassays (for example indirect immunofluorescence or ELISA), the test helps identify immune activity against hepatic structures and is an important marker used in the diagnostic work-up of autoimmune hepatitis type 1.

This home ASMA test provides convenient UAE sample collection with laboratory-grade analysis and specialist reporting to aid early immune profiling. It is most useful when investigating unexplained abnormal liver function tests or symptoms suggestive of autoimmune liver disease, but results must be interpreted alongside clinical findings and other investigations (ANA, immunoglobulin G levels, viral serology and, when indicated, liver biopsy).

• Smooth Muscle Antibody (ASMA) — IgG titer
• Anti–F‑actin (anti‑actin) antibodies
• ASMA result: Qualitative (Positive / Negative) and reported titre

• Unexplained elevation of liver enzymes (ALT, AST)
• Clinical signs of liver disease: jaundice, fatigue, dark urine, pruritus
• Suspicion of autoimmune hepatitis during hepatology work-up
• Presence of other autoimmune conditions with abnormal LFTs
• Preliminary evaluation when viral and metabolic causes have been excluded

• Early detection of autoimmune liver autoantibodies to guide diagnosis
• Convenient at‑home blood collection with sample pickup across Dubai and the UAE
• Laboratory-standard analysis with clear titre reporting
• Fast results with specialist-ready reports to support clinician referral
• Reduces need for immediate hospital visits during initial screening

• At‑home venous blood collection by a trained phlebotomist (serum sample)
• No fasting required; standard preparation is sufficient
• Inform the collector/clinician about current medications and recent blood transfusions
• Results should be reviewed by a physician or hepatology specialist for accurate interpretation