
HEPATITIS B CORE TOTAL ANTIBODY
Author Details
Written By
Dr. Arjun Nair
MD (Internal Medicine)
Supervised By
Dr. Kavya Reddy
MD (Biochemistry)





HEPATITIS B CORE TOTAL ANTIBODY
At-home Hepatitis B core total antibody test to detect past or current exposure, providing reliable results and clinical guidance across Dubai and UAE.
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Know More About HEPATITIS B CORE TOTAL ANTIBODY
The Hepatitis B core total antibody test (Anti-HBc total) is a serology test that detects antibodies to the hepatitis B core antigen, measuring both IgM and IgG to indicate past or current exposure to hepatitis B virus. It is performed on a blood sample and reported qualitatively (reactive/non-reactive); presence of anti-HBc indicates prior infection rather than vaccine-induced immunity, since vaccination produces anti-HBs but not anti-HBc. This at-home test in Dubai and across the UAE is collected by a certified phlebotomist and delivered to accredited laboratories, with results and clinical guidance provided to help inform follow-up testing and medical decisions.
The Anti-HBc total test is useful for diagnosing recent or resolved HBV infection when used alongside HBsAg and anti-HBs tests, and for screening before immunosuppressive therapy, organ transplant, or blood product exposure. It is recommended for individuals with abnormal liver enzymes, those with known exposure risks (needlestick, unprotected sex, household contact), people unsure of their vaccination or infection history, and patients undergoing treatments that may reactivate latent HBV.
Parameters Measured
- Hepatitis B core total antibody (Anti-HBc total)
- Anti-HBc IgM (acute infection marker)
- Anti-HBc IgG (past/chronic infection marker)
- Qualitative result: Reactive / Non-reactive
When to Test it?
- After known or suspected exposure to hepatitis B (needlestick, sexual contact)
- Unexplained elevation of liver enzymes (ALT/AST)
- Prior to immunosuppressive therapy, chemotherapy, or organ transplantation
- When distinguishing past infection from vaccine-induced immunity
- Part of hepatitis panel when HBsAg or anti-HBs results are unclear
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Benefits Includes:
- Detects past or recent hepatitis B exposure not identified by vaccination status
- Helps guide further testing (HBsAg, anti-HBs) and clinical decisions
- Convenient at-home collection with accredited lab analysis across Dubai and UAE
- Rapid, reliable qualitative reporting with follow-up clinical guidance available
- Useful for screening before treatments that risk HBV reactivation
Doctor Recommended Checkups
Test requirements:
- At-home venous blood collection by a certified phlebotomist (sample transported to an accredited lab)
- No fasting required for this serology test
- Inform the collector about recent hepatitis B vaccination, immunoglobulin, or antiviral therapy
- Provide valid Emirates ID and consent at time of sample collection (appointment required)
Author Details
Written By
Dr. Arjun Nair
MD (Internal Medicine)
Supervised By
Dr. Kavya Reddy
MD (Biochemistry)

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