MTHFR Gene analysis - 2 exons (5 & 8)

This at‑home MTHFR gene analysis (exons 5 & 8) detects key genetic variants that can affect folate metabolism and homocysteine regulation, providing genotype information that may influence nutritional and medication decisions. A simple cheek swab collected at home is analysed by clinical laboratories serving the UAE, and the report highlights relevant findings and practical considerations for folate supplementation, pregnancy planning and drugs impacted by methylation. Results are presented with clear interpretation and we recommend reviewing them with your UAE healthcare provider before making any changes to treatment or supplements.

• MTHFR — Exon 5: c.677C>T (p.Ala222Val / C677T)
• MTHFR — Exon 8: c.1298A>C (p.Glu429Ala / A1298C)
• Genotype/zygosity — homozygous, heterozygous, wild‑type
• Allele status — presence/absence of detected variants

• Targets MTHFR variants in exons 5 and 8 that can impair folate conversion and raise homocysteine levels
• May inform personalized folate/methylfolate supplementation for pregnancy planning and reducing neural tube defect risk
• Supports medication decisions by identifying variants that can influence response or toxicity to folate‑interacting drugs (e.g., methotrexate)
• Convenient at‑home sample collection across the UAE with secure laboratory analysis and clinician‑ready reports
• Provides actionable genetic interpretation to assist clinicians in cardiovascular and metabolic risk management

• Detects key MTHFR variants in exons 5 & 8 that impact folate metabolism
• Assesses potential for elevated homocysteine and associated cardiovascular/neuro risks
• Supports personalized folate and B12 supplementation and medication adjustment decisions
• Convenient at‑home sample collection with courier pickup and Dubai‑certified laboratory testing
• Delivered as a concise clinical report with interpretation suitable for UAE healthcare providers

• At‑home cheek swab testing targeting MTHFR exons 5 and 8 to detect clinically relevant variants
• Clinician‑level report with actionable interpretation for folate metabolism, supplementation and medication considerations
• Suitable for preconception planning, pregnancy care and chronic disease management with results usable by UAE healthcare providers
• Secure, CLIA‑grade laboratory processing with nationwide home collection and rapid turnaround