
Parietal Cell Antibody
Author Details
Written By
Dr. Arjun Nair
MD (Internal Medicine)
Supervised By
Dr. Ananya Rao
MD (Microbiology)





Parietal Cell Antibody
Home parietal cell antibody testing to detect autoimmune gastritis and B12 absorption issues, with accredited Dubai labs and fast, reliable results.
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Know More About Parietal Cell Antibody
The Parietal Cell Antibody test detects autoantibodies directed against gastric parietal cells—cells that produce stomach acid and intrinsic factor, a protein essential for vitamin B12 absorption. This serum-based immunoassay (typically reporting IgG antibodies and a titre) helps identify autoimmune gastritis and the risk of pernicious anemia by indicating immune-mediated damage to the stomach lining.
This test is useful for patients with unexplained vitamin B12 deficiency, macrocytic anemia, or neurological symptoms suggestive of B12 malabsorption, and for people with other autoimmune conditions. Offered as a convenient home collection service with accredited Dubai labs, results are reported quickly to support timely clinical decisions such as B12 replacement therapy, further gastroenterology evaluation, or testing for intrinsic factor antibodies and endoscopic assessment when indicated.
Parameters Measured
- Anti‑Parietal Cell Antibody (IgG)
- Parietal Cell Antibody Titre / Result
- Laboratory interpretive comment / reference range
When to Test it?
- Unexplained vitamin B12 deficiency or macrocytic anemia
- Neurological symptoms: numbness, paresthesia, gait disturbance, cognitive changes
- Chronic gastritis or persistent upper abdominal discomfort with suspected autoimmune cause
- Personal or family history of autoimmune disease (e.g., thyroiditis, type 1 diabetes)
- Assessment before or during evaluation for pernicious anemia
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Benefits Includes:
- Identifies autoimmune gastritis as a cause of B12 malabsorption
- Helps guide targeted treatment decisions (B12 supplementation, specialist referral)
- Convenient at‑home blood collection with accredited Dubai laboratories
- Fast, reliable results and professional laboratory interpretation
- Supports preventive care by detecting risk before significant anemia or neurological damage
Doctor Recommended Checkups
Test requirements:
- At‑home venous blood sample collection by a certified phlebotomist
- No fasting required for the antibody test
- Inform the clinician/lab about recent B12 injections or immunosuppressive medications
Author Details
Written By
Dr. Arjun Nair
MD (Internal Medicine)
Supervised By
Dr. Ananya Rao
MD (Microbiology)

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