ZINC TRANSPORTER 8 ABS

The ZINC TRANSPORTER 8 ABS test detects autoantibodies directed against the Zinc Transporter 8 (ZnT8) protein, a beta‑cell membrane antigen. It is performed on a serum sample using sensitive immunoassays to identify immune-mediated beta‑cell autoimmunity associated with type 1 diabetes and latent autoimmune diabetes in adults (LADA).

This home collection test is useful for early identification of autoimmune diabetes risk, aiding clinicians in distinguishing autoimmune from type 2 diabetes and in guiding treatment and monitoring decisions. Samples are collected at home by trained phlebotomists across Dubai and the UAE, with fast laboratory turnaround and physician consultation recommended for interpretation and next steps.

Test reports typically provide a quantitative antibody titre and a qualitative interpretation (negative, borderline, or positive). A positive ZnT8 antibody result supports an autoimmune diagnosis but should be interpreted alongside clinical findings and other markers (e.g., GAD65, IA-2, C‑peptide); it does not alone determine treatment without medical review.

• Zinc Transporter 8 Antibodies (ZnT8‑Ab)
• ZnT8 Antibody Titre (U/mL)
• Qualitative Result (Negative / Borderline / Positive)

• New‑onset hyperglycaemia in children, adolescents, or young adults
• Atypical diabetes presentation or lean adults with suspected LADA
• To differentiate autoimmune diabetes from type 2 diabetes
• First‑degree relatives of individuals with type 1 diabetes for risk assessment
• Rapid decline in glycaemic control or unexpected insulin dependence

• Early detection of autoimmune beta‑cell injury risk
• Helps differentiate autoimmune versus non‑autoimmune diabetes for targeted therapy
• Convenient at‑home sample collection across Dubai and the UAE
• Quantitative and qualitative results to support clinical decision‑making
• Facilitates family risk counselling and timely specialist referral

• At‑home venous blood collection by a certified phlebotomist (serum sample)
• No fasting required unless instructed otherwise by your clinician
• Provide recent medical history and current medications at time of collection
• Results reviewed and interpreted by a licensed healthcare professional in the UAE